Natural Quorum Sensing Inhibitors of P. aeruginosa

Project Summary

Pyoverdin is a fluorescent byproduct of bacterial communication in the bacterium P. aeruginosa, which causes pneumonia in cystic fibrosis patients. Different natural substances were tested to see if they inhibited the bacterial communication. Successful substances included black tea, white tea, and coffee.

Personal Note

This was my first ever official biomedical research project that I completed in high school. Under the guidance of Dr. Richard Myers, I entered this poster into an international science competition called BioGENEius and actually managed to win an honorable mention award! The organization flew me and my dad out to San Diego for a couple of days, and I presented this poster to world-renowned scientists and physicians. It was definitely very exciting and I highly recommend other precocious high school students to apply!